Suche
  • OARCB - Interdiziplinäre Arthroseforschung
Suche Menü

Dr. Uta Helmrich, PhD

Dr. Uta Helmrich joined the Osteoarthritis Research Center at the University Hospital Basel as a Research Scientist in 2012. After completing her diploma thesis at the Laboratoire de Génétique Moléculaire de la Neurotransmission et des Processus Neurodégénéraifs (CNRS) in Paris, she received a graduate degree in Biology from the Eberhard Karls Universität Tübingen, Germany. She then started her PhD in Medical Biology at the Institute for Surgical Research and Hospital Management at the University of Basel, Switzerland, which she obtained in 2011.

 Research interests

  • Cellular participants and molecular mechanisms in bone homeostasis
  • Causes and results of disrupted bone homeostasis in the case of osteoarthritis
  • Therapeutical approaches to treat osteoarthritis

 Selected Publications

  • U. Helmrich, N. Di Maggio, A. Marsano, S. Güven, E. Groppa, M. Heberer, A. Scherberich, I.  Martin and A. Banfi (submitted) VEGF-expressing mesenchymal stem cells for rapid vascularization of tissue-engineered bone grafts. Biomaterials
  • L. Melly, A. Marsano, A. Frobert, S. Boccardo, U. Helmrich, M. Heberer, F. Eckstein, TP. Carrel, MN. Giraud, HT. Tevaearaic and A. Banfi (2012) Controlled angiogenesis in the heart by cell-based expression of specific VEGF levels. Human Gene Therapy Methods 23(5):346-56.
  • U. Helmrich, A. Marsano, L. Melly, T. Wolff, L. Christ, M. Heberer, A. Scherberich, I. Martin and A. Banfi (2012) Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification. Tissue Engineering 18(4):283-92.
  • T. Wolff, E. Mujagic, R. Gianni-Barrera, P. Fueglistaler, U. Helmrich, H. Misteli, L. Gurke, M. Heberer and A. Banfi (2012) FACS-purified myoblasts producing controlled VEGF-levels induce safe and stable angiogenesis in chronic hind limb ischemia. Journal of Cellular and Molecular Medicine 16(1):107-17.